{"id":5235,"date":"2014-12-12T10:00:26","date_gmt":"2014-12-12T18:00:26","guid":{"rendered":"http:\/\/sop.washington.edu\/?p=5235"},"modified":"2017-01-04T15:45:19","modified_gmt":"2017-01-04T23:45:19","slug":"taking-medication-prescribed-critical-drugs-effectiveness","status":"publish","type":"post","link":"https:\/\/staff.washington.edu\/twentzel\/wordpress\/taking-medication-prescribed-critical-drugs-effectiveness\/","title":{"rendered":"Why the Bad Taste? Dr. Joanne Wang\u2019s Team Finds a Reason"},"content":{"rendered":"<div><a href=\"\/wp-content\/uploads\/Drugs-Yuck.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-4687\" src=\"\/wp-content\/uploads\/Drugs-Yuck-300x225.jpg\" alt=\"Drugs-Yuck\" width=\"300\" height=\"225\" srcset=\"https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Drugs-Yuck-300x225.jpg 300w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Drugs-Yuck-250x188.jpg 250w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Drugs-Yuck-108x81.jpg 108w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Drugs-Yuck.jpg 613w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/div>\n<div>TAKING A MEDICATION AS PRESCRIBED IS CRITICAL to a drug\u2019s effectiveness. But for some people, taking medications literally turns their stomach \u2013 and if a medication leaves a persistently bitter taste, many people, especially children and elderly patients, will take it inconsistently or not at all. In the online Journal of Biological Chemistry, Joanne Wang\u2019s research team in the University of Washington School of Pharmacy describe a novel mechanism for active drug accumulation and secretion in salivary gland epithelial cells that leads to the lingering bad taste of metformin, a frontline prescription drug used to treat type 2 diabetes.\u00a0 <a href=\"http:\/\/hsnewsbeat.uw.edu\/story\/why-face-uw-researchers-find-clue-drugs-bad-taste\" target=\"_blank\">Full story&#8230;<\/a><\/div>\n<p>&nbsp;<\/p>\n<p><a href=\"\/department-of-pharmaceutics\/department-info-2\/department-news-2\/\">Link to Pharmaceutics archived news<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>TAKING A MEDICATION AS PRESCRIBED IS CRITICAL to a drug\u2019s effectiveness. But for some people, taking medications literally turns their stomach \u2013 and if a medication leaves a persistently bitter taste, many people, especially children&#8230;<\/p>\n","protected":false},"author":3,"featured_media":4687,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[33,31],"tags":[],"class_list":["post-5235","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pceut-news","category-sop-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Why the Bad Taste? 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But for some people, taking medications literally turns their stomach \u2013 and if a\" \/>\n<meta property=\"og:url\" content=\"https:\/\/staff.washington.edu\/twentzel\/wordpress\/taking-medication-prescribed-critical-drugs-effectiveness\/\" \/>\n<meta property=\"og:site_name\" content=\"School of Pharmacy\" \/>\n<meta property=\"article:publisher\" content=\"http:\/\/www.facebook.com\/UWSOP\" \/>\n<meta property=\"article:published_time\" content=\"2014-12-12T18:00:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-01-04T23:45:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Drugs-Yuck.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"613\" \/>\n\t<meta property=\"og:image:height\" content=\"461\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Tim Wentzel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UW_Pharmacy\" \/>\n<meta name=\"twitter:site\" content=\"@UW_Pharmacy\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Tim Wentzel\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/staff.washington.edu\\\/twentzel\\\/wordpress\\\/taking-medication-prescribed-critical-drugs-effectiveness\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/staff.washington.edu\\\/twentzel\\\/wordpress\\\/taking-medication-prescribed-critical-drugs-effectiveness\\\/\"},\"author\":{\"name\":\"Tim Wentzel\",\"@id\":\"https:\\\/\\\/staff.washington.edu\\\/twentzel\\\/wordpress\\\/#\\\/schema\\\/person\\\/21859bae0c32073fc2c8d833a054b09f\"},\"headline\":\"Why the Bad Taste? 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