{"id":21320,"date":"2019-04-23T15:23:51","date_gmt":"2019-04-23T22:23:51","guid":{"rendered":"https:\/\/sop.washington.edu\/?p=21320"},"modified":"2026-04-01T13:11:01","modified_gmt":"2026-04-01T20:11:01","slug":"henderson-wins-poster-award-at-national-aspet-conference","status":"publish","type":"post","link":"https:\/\/staff.washington.edu\/twentzel\/wordpress\/henderson-wins-poster-award-at-national-aspet-conference\/","title":{"rendered":"Henderson wins poster award at national AsPET Conference"},"content":{"rendered":"<figure id=\"attachment_21322\" aria-describedby=\"caption-attachment-21322\" style=\"width: 750px\" class=\"figure figure-caption wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full-content wp-image-21322\" src=\"https:\/\/sop.washington.edu\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-750x564.png\" alt=\"Lindsay Henderson with her award-winning poster\" width=\"750\" height=\"564\" srcset=\"https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-750x564.png 750w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-300x226.png 300w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-768x578.png 768w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-1024x771.png 1024w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-375x282.png 375w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-1140x858.png 1140w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019-108x81.png 108w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Poster_Ap2019.png 2048w\" sizes=\"auto, 100vw\" \/><figcaption id=\"caption-attachment-21322\" class=\"wp-caption-text\">Lindsay Henderson with her award-winning poster,\u00a0&#8220;Functional Characterization of Novel CYP2C9 Variants Found in an Alaska Native Population&#8221; <\/figcaption><\/figure>\n<p>Congratulations to PharmD and Pharmaceutics PhD student Lindsay Henderson who received the 2nd place graduate student poster presentation award for the Drug Metabolism and Disposition Division of ASPET (American Society for Pharmacology and Experimental Therapeutics).<\/p>\n<figure id=\"attachment_21321\" aria-describedby=\"caption-attachment-21321\" style=\"width: 225px\" class=\"figure figure-caption wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-21321 size-medium\" src=\"https:\/\/sop.washington.edu\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19-225x300.jpg\" alt=\"Lindsay Henderson, here pictured with Med Chem Professor Allan Rettie\" width=\"225\" height=\"300\" srcset=\"https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19-225x300.jpg 225w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19-768x1024.jpg 768w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19-375x500.jpg 375w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19-750x1000.jpg 750w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19-1140x1520.jpg 1140w, https:\/\/staff.washington.edu\/twentzel\/wordpress\/wp-content\/uploads\/Lindsay_Henderson_ASPET_Award_SP19.jpg 1537w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><figcaption id=\"caption-attachment-21321\" class=\"wp-caption-text\">Lindsay Henderson, here pictured with Med Chem Professor Allan Rettie <\/figcaption><\/figure>\n<p>Her poster titled, \u201cFunctional Characterization of Novel CYP2C9 Variants Found in an Alaska Native Population,\u201d focuses on genetic polymorphisms in CYP2C9, an important cytochrome P450 responsible for the metabolism of medications across many therapeutic classes including non steroidal anti-inflammatories, angiotensin II blockers, as well as narrow therapeutic index drugs such as (S)-warfarin and phenytoin.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p>Comprehensive\u00a0in vitro\u00a0experiments were performed to elucidate the function of novel CYP2C9 protein variants found in an Alaska Native population.<\/p>\n<p>The team&#8217;s findings suggest that carriers of the\u00a0CYP2C9 N218I\u00a0and\u00a0M1L\u00a0variant alleles would be at risk of exacerbated therapeutic effects from narrow therapeutic index drugs that rely on CYP2C9 for their metabolic clearance.<\/p>\n<p>Her co-authors include UWSOP researchers, <strong>Matthew G McDonald, Catherine K Yeung, <\/strong>&#8217;05, <strong>Allan E Rettie, <\/strong>and<strong> Kenneth E Thummel<\/strong>, who served as Senior Author.<\/p>\n<p>Congratulations, Lindsay!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to PharmD and Pharmaceutics PhD student Lindsay Henderson who received the 2nd place graduate student poster presentation award for the Drug Metabolism and Disposition Division of ASPET (American Society for Pharmacology and Experimental Therapeutics)&#8230;.<\/p>\n","protected":false},"author":3,"featured_media":21326,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[32,33,31],"tags":[],"class_list":["post-21320","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medchem-news","category-pceut-news","category-sop-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Henderson wins poster award at national AsPET Conference - School of Pharmacy<\/title>\n<meta name=\"description\" content=\"Congratulations to PharmD and Pharmaceutics PhD student Lindsay Henderson who received the 2nd place graduate student poster presentation award for the\" 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