{"id":678,"date":"2014-06-09T14:26:15","date_gmt":"2014-06-09T21:26:15","guid":{"rendered":"http:\/\/sop.washington.edu\/?page_id=678"},"modified":"2026-03-31T15:27:31","modified_gmt":"2026-03-31T22:27:31","slug":"alumni","status":"publish","type":"page","link":"https:\/\/staff.washington.edu\/twentzel\/wordpress\/department-of-pharmaceutics\/students-fellows\/alumni\/","title":{"rendered":"Alumni"},"content":{"rendered":"<p>Adkison, Kimberly (1994)<br \/>\nThesis: Central Nervous System Transport of Valproic Acid<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Alade, Nathan (2023)<br \/>\nThesis: Precision Approaches for Assessing Complex Pharmacogenomic Traits in Vitamin K Metabolism<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Amore, Benny (1996)<br \/>\nThesis: Mechanism of Carbamazepine Teratogenictity<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Anderson, Gail (1987)<br \/>\nThesis: The Interaction of Phenobarbital and Valproic Acid in the Rat<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Andrada, Dominic (1999)<br \/>\nThesis: Liposome-Anchored Vascular Endothelial Growth Factor (VEGF) Peptide Analog<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Anoshchenko, Lena (2021)<br \/>\nThesis:Prediction of Human Fetal Exposure to P-gp Substrate Drugs Using the Proteomics-informed Relative Expression Factor Approach and PBPK Modeling and Simulation.<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Arian, Christopher (2024)<br \/>\nThesis: Development and Characterization of a Human Intestinal Organoid Monolayer Model to Predict Oral Drug Disposition<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Arends, Rosalin (1998)<br \/>\nThesis: Pharmacokinetics and Pharmacodynamics of Opioid Analgesics<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Bajpai, Manoj (1996)<br \/>\nThesis: Metabolic Isozymes of Phenytoin and Their Roles in Its Drug Interactions<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Beaumier, Paul (1981)<br \/>\nThesis: The Use of Radioisotopes as Probes for the Characterization of Liposomal Behavior in Vivo and in Vitro<br \/>\nThesis Advisor: Karl Hwang, Ph.D.<\/p>\n<p>Bergagnini-Kolev,Mackenzie (2020)<br \/>\nThesis:Altered Vitamin D Metabolism in Health and Disease<br \/>\nThesis advisor: Yvonne Lin, Ph.D.<\/p>\n<p>Bethune, Claudette (1999)<br \/>\nThesis: The Role of Drug-Lipid Interactions in Biodistribution and Therapeutic Effects for Drug Incorporated into Lipsomes<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Buchanan, Megan (2010)<br \/>\nThesis: The Genotype-Phenotype Relationship between Vitamin D Receptor Polymorphisms and Tacrolimus Level-Dose Ratios<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Carlson, Sonia (2000)<br \/>\nThesis: A New Data Mining Tool: The Metabolic Drug Interaction Database with Enhanced Search Capability<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Cesar, Francine (2021)<br \/>\nThesis: Development of a Cystic Fibrosis Microphysiological Model of the Kidney Proximal Tubule<br \/>\nThesis Advisor: Edward Kelly, Ph.D.<\/p>\n<p>Chang, Shih-Ling (1983)<br \/>\nThesis: Mechanism of the Interaction Between Valproic Acid and Carbamazepine in the Rat<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Chen, Freddy (2020)<br \/>\nThesis: A Pharmacometrics Approach to Understanding Drug Disposition and Drug Interactions in Healthy Individuals and Patients Undergoing Roux-en-Y Gastric Bypass<br \/>\nThesis Advisor: Yvonne Lin, Ph.D.<\/p>\n<p>Chen, Xin (2025)<br \/>\nThesis: <span data-olk-copy-source=\"MessageBody\">(-)-\u03949-tetrahydrocannabinol and pregnancy: transporter-mediated\u00a0tissue distribution\u00a0and\u00a0drug\u00a0interactions<\/span><br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Chen, Xinyue (2024)<br \/>\nThesis: Characterization of an Orthotopic Pancreatic Ductal Adenocarcinoma (PDAC) Tumor Model and Targeted Therapeutics for PDAC<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Chen, Zhiqian (2025)<br \/>\nThesis: Optimizing a turnkey drug-gene synchronous delivery nanoplatform against metastatic breast cancer<br \/>\nThesis Advisor: Qingxin Mu, Ph.D.<\/p>\n<p>Chien, Jenny (1997)<br \/>\nThesis: Pharmacokinetics of Drug Interactions Due to Ligand Stabilization Of CYP2EI<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Chien, Yuting (Emily) (2025)<br \/>\nThesis: Development of KRAS-Targeting siRNA and Chemotherapy Co-Delivery Chitosan Nanoparticles for Enhanced Treatment of Pancreatic Cancer<br \/>\nThesis Advisor: Qingxin Mu, Ph.D.<\/p>\n<p>Crouthamel, Matthew (2010)<br \/>\nThesis: The Impact of Genetic Variation and Tissue Selective Expression of the Multidrug Resistant Transporter P-Glycoprotein: Evaluation in Recombinant Cells and Development of Transgenic Mouse Models<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Dahlin, Amber (2008)<br \/>\nThesis: Molecular cloning and characterization of the murine plasma membrane monoamine transporter (Slc29a4): function, expression and physiological significance<br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Dai, Yang (2006)<br \/>\nThesis: Impact of the CYP3A5 Polymorphism on the Metabolic Disposition of the Calcineurin Inhibitors<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Emery, Maurice (1999)<br \/>\nThesis: Aspects of Human CYP2E1 Regulation in Health and Disease<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Endres, Chris (2008)<br \/>\nThesis: The Role of the Equilibrative Nucleoside Transporter 1 (ENT1) on the Absorption and Disposition of Ribavirin in the Mouse<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Endsley, Aaron (2011)<br \/>\nThesis: Targeted Antiviral Drug Delivery to HIV Target Cells in Lymphoid Tissue<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Erickson, Inga (2024)<br \/>\nThesis: Intestinal Dysbiosis Alters Seizure Burden and Antiseizure Medicine Activity Profile in the Theiler\u2019s Virus Model of Acute Encephalitis<br \/>\nThesis Advisor: Melissa Barker-Haliski, Ph.D. and Kenneth Thummel, Ph.D.<\/p>\n<p>Fisher, Jeannine (1998)<br \/>\nThesis: CYP3A-Dependent Midazolam Metabolism in Modified Caco-2-cells<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Gibbs, John (1998)<br \/>\nThesis: Age-Dependent Busulfan Disposition and Its relation to GSTAI-1 Expression<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Gibbs (Robinson), Megan (1999)<br \/>\nThesis: Characterization of Drug Interactions Involving Intestinal CYP3A: Role of Sequestration and Protein Binding<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Griffin, James Ian (2023)<br \/>\nThesis: Advancing Treatments for Leukemia and Metastatic Pancreatic Cancer: Targeted Drug Combination Nanoparticles and Subsequent Synchronized Delivery of Multiple Associated Small Molecule Drugs<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Han,Lyrialle (2020)<br \/>\nThesis: Drug Disposition during Pregnancy:\u00a0Transport, Metabolism, and the Gut Microbiome<br \/>\nThesis advisor: Qingcheng Mao, Ph.D.<\/p>\n<p>Hao, Tianran (2023)<br \/>\nThesis: Dysregulation of Human Hepatic Drug Transporters by Proinflammatory Cytokines<br \/>\nThesis Advisor: Qingcheng Mao, Ph.D. and Jashvant Unadkat, Ph.D.<\/p>\n<p>Hoekman, John(2010)<br \/>\nThesis: The Impact of Enhanced Olfactory Deposition and Retention on Direct Nose-to-Brain Drug Delivery<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Hsiao, Peng (2011)<br \/>\nThesis: Can P-glycoprotein based drug interactions at the Human Blood-Brain Barrier be Predicted from in vitro and rat in vivo studies?<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Hurst, Susan (1999)<br \/>\nThesis: Roles of Cytochromes P450 and Microsomal Epoxide Hydrolase In Drug-Drug Interactions Involving Valproic Acid and its Analogues<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Huang,Weili (2006)<br \/>\nThesis: Impact of CYP3A5 and P-glycoprotein on Hepatic and Renal Drug Clearance<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Huang, Weize (2020)<br \/>\nThesis: Mechanistic Physiologically Based Pharmacokinetic (PBPK) Modeling of Renal and Systemic Disposition of Drugs and Metabolites<br \/>\nThesis advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Jefferis, Marlene (1996)<br \/>\nAdvisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Jones-Isaac, Kendan (2023)<br \/>\nThesis: Evaluating the Impact of Microgravity on a Microphysiologic Model of Kidney Stone Disease<br \/>\nThesis Advisor: Edward Kelly, Ph.D.<\/p>\n<p>Jung, Elijah (2026)<br \/>\nThesis: <span data-olk-copy-source=\"MessageBody\">Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta<\/span><br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Kavanagh, Ronald (1995)<br \/>\nThesis: Evaluation of Models to Study Mechanisms of Enhanced Xenobiotic Sulfation in Cystic Fibrosis<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Kerr, Brad (1988)<br \/>\nThesis: Role of Epoxide Hydrolase in Carbamazepine Epoxide Drug Interactions<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Kim, Chungsook (1985)<br \/>\nThesis: Pharmacokinetic-Aspects of Sulfoconjugation<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Kinman, Loren (2005)<br \/>\nThesis: Lipid-Drug Association Enhanced HIV-1 Protease Inhibitor Indinavir Localization in Lymphoid Tissues<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Koch, Kevin (1985)<br \/>\nThesis: Role of Beta-Oxidation in Valproic Acid Clearance<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Kroetz, Deanna H. (1990)<br \/>\nThesis: Inhibition of Human Liver Microsomal Epoxide Hydrolase<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Kumar, Aditya (2023)<br \/>\nThesis: Quantification and Prediction of Human Fetal (-)-delta-9- tetrahydrocannabinol (THC)\/11-OH-THC Exposure to Inform Neurodevelopmental Toxicity of Cannabis<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>LaFrance, Jeffrey (2024)<br \/>\nThesis: Study of the Impact of Isotretinoin Administration on CYP3A4 Activity Using 6\u03b2-Hydroxylation of Cortisol and Cortisone as Endogenous Biomarkers<br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Lalovic, Bojan (2003)<br \/>\nThesis: Pharmacokinetics and Pharmacodynamics of Oral oxycodone: Role of Active Metabolites<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Lane, Elizabeth (1981)<br \/>\nThesis: Studies on Parent-Metabolite Relationships for Cinromide and two Metabolites<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Laganiere, Sylvie (1986)<br \/>\nThesis: Disposition Kinetics of Propranololin Uremia<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Lau, S.W. Johnny (1985)<br \/>\nThesis: Nasal Absorption of Diazepam and Lorazepam<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Lee, Ahram (2025)<br \/>\nThesis: <span data-olk-copy-source=\"MessageBody\">Use of a Genetically Modified Cell Culture Model to Investigate Human Breast Cancer Resistance Protein-mediated Milk Secretion of Drugs<\/span><br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Lee, Caroline (1993)<br \/>\nThesis: Effects of Methylxanthines on Acetaminophen Reactive Metabolite Formation<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Lee, Chi-Hyun (1990)<br \/>\nThesis: Uremia Induced Intrinsic Defect in Propranolol Metabolism<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Lehmann, Paul (1986)<br \/>\nThesis: Percutaneous Absorption of Retinoids<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Li, Shuang Wu (Cheryl) (2002)<br \/>\nThesis: Transport of Valproic Acid in the Brain: Involvement of Multiple Organic Anion Transporters<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Li, Meng (2007)<br \/>\nThesis: UTI Antibiotics: Mechanism of Transport and In Vivo Interaction with Cranberry Juice<br \/>\nThesis Advisor: Joanne Wang , Ph.D.<\/p>\n<p>Lidberg, Kevin (2021)<br \/>\nThesis: Human serum components drive primary proximal tubule epithelial cells toward a proinflammatory phenotype<br \/>\nThesis Advisor: Edward Kelly, Ph.D.<\/p>\n<p>Lin, Jasmie (1993)<br \/>\nThesis: Mechanisms of Valproic Acid Associated Hepatotoxicity<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Lin, Yi-Xin (1997)<br \/>\nThesis: Steroid Hormones and Anti-epileptic Drugs<br \/>\nThesis Advisor: Gail Anderson, Ph.D.<\/p>\n<p>Lin, Yvonne (2002)<br \/>\nThesis: Variability in CYP3A Expression and Metabolism: Influence of Genetics and Probe Substrate Selection<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Lockhart, Catherine (2016)<br \/>\nThesis: Function and Regulation of Cytochrome P450 4V2 and the Implications in Bietti\u2019s Crystalline Dystrophy<br \/>\nThesis Advisor: Edward Kelly, Ph.D.<\/p>\n<p>Lopez Quinones, Antonio (2021)<br \/>\nThesis: The roles of the polyspecific organic cation transporters in the disposition of mIBG<br \/>\nand implications for toxicities and drug interactions<br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Loughren, Michael (2008)<br \/>\nThesis: Herb-Opioid Interactions Involving Modulation of Cytochrome P450 Enzymes and P-Glycoprotein<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Madani, Soraya (1998)<br \/>\nThesis: Comparative Metabolic Kinetics of Hepatic and Intestinal CYP2D6 And CYP3A: In Vitro Probe Studies with Metoprolol &amp; Terfenadine<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Mahadeo, Anish (2025)<br \/>\nThesis: Characterization of Understudied Risk Factors in Chronic Kidney Disease<br \/>\nThesis Advisor: Ed Kelly, Ph.D.<\/p>\n<p>Manyike, Peter (1998)<br \/>\nThesis: CYP2E1: Mechanism of Induction by Isoniazid and Role in Acetaminophen Oxidation<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Marathe (Karnik), Punit (1989)<br \/>\nThesis: Investigation of Mechanism by which Thermal Injury Produces Resistance to Nonpolarizing Muscle Relaxants<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Mathias, Anita (2004)<br \/>\nThesis: Mechanisms of Accelerated Clearance of Anti-HIV Protease Inhibitors in Pregnancy<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>McConn II, Donavon (2001)<br \/>\nThesis: Cytochromes P450 3A4 and 3A5: Metabolic and Inhibitory Differences<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>McConnachie, Lisa (2001)<br \/>\nThesis: Interindividual Variability in Drug Metabolism: CYP2D6 as a Model Enzyme.<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Moss, Aaron (2010)<br \/>\nThesis: The role of nucleoside transporters in the absorption and distribution of the nucleoside drugs ribavirin and gemcitabine<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>O&#8217;Connor-Semmes, Robin (1988)<br \/>\nThesis: Nonlinear Pharmacokinetics and Anticonvulsant Efficacy of E &#8211; (2 Valproic Acid in the Rat<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Paine, Mary (1997)<br \/>\nThesis: CYP3A-Dependent First-Pass Metabolism: Intestine vs. Liver<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Pulham, David (1991)<br \/>\nThesis: Bioavailability Assessment Based on Parent Drug and Metabolite Concentrations: Statistical Advantage in the Well-Stirred Model<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Qiu, Ruolun (2003)<br \/>\nThesis: ABCC2(cMOAT): Role in hydroxycyclophosphamide elimination from the liver and survival of high dose cyclophosphamide regimens.<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Qiu, Wei (2000)<br \/>\nThesis: In Vitro and In Vivo Methods for Predictions of CYP2C9 Kinetic Parameters for Phenytoin and Tolbutamide<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Ren, Aaron Gang (2005)<br \/>\nThesis: Immunosuppressants Used in the Conditioning Regimens for Hematopoietic Stem Cell Transplantation<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Ren, Song (1999)<br \/>\nThesis: Metabolism of Cyclophosphamide: Implications for Hematopoietic Stem Cell Transplantation<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Rohatgi, Priyanka (2010)<br \/>\nThesis: Characterization of a Lamellar Ichthyosis-Associated P450, CYP4F22 and Bietti\u2019s Crystalline Dystrophy- Associated P450, CYP4v3<br \/>\nThesis Advisor: Ed Kelly, Ph.D.<\/p>\n<p>Roskos, Lorin (1994)<br \/>\nThesis: Inhibition of Hepatic Metabolism of (S)-Propanolol by Uremic Blood Constituents<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Salvador Vieira , Let\u00edcia (2023)<br \/>\nThesis: The Polyspecific Organic Cation Transporters: Role in Cancer Drug Targeting, Xenobiotic Disposition, and Drug-drug Interactions<br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Sawyer, Kevin (1999)<br \/>\nThesis: Phenytoin Metabolism by CYP3A7: Implications for Fetal Hydantoin Syndrome<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Scott, Ariel Michelle (2023)<br \/>\nThesis: Development of Long-acting Formulation of Dolutegravir Sodium for Human Immunodeficiency Virus<br \/>\nAdvisor: Rodney Ho, Ph.D.<\/p>\n<p>Senn, Taurence (2000)<br \/>\nThesis: The Differential Effects of Calcitriol and Paricalcitol on CYP3A And P-glycoprotein Expression<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Shan, Amelia (2024)<br \/>\nThesis: <span data-olk-copy-source=\"MessageBody\">Impact of Aging and Sex on the Expression and Function of Xenobiotic Transporters at the Blood-Cerebrospinal Fluid Barrier<\/span><br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Shum, Sara (2020)<br \/>\nThesis<img alt=\"\" \/>:\u00a0<img alt=\"\" \/>Application of in vitro, in silico, and in vivo Methodologies to Quantitatively Study Maternal-Fetal Disposition of Xenobiotics<br \/>\nAdvisor: Nina Isoherranen, Ph.D.<\/p>\n<p style=\"text-align: left;\">Steinbronn, Claire (2023)<br \/>\nThesis: Static and Dynamic Forms to Determine DDI Potential and Sources of Pharmacokinetic Variability<br \/>\nThesis Advisor: Samuel Arnold, Ph.D.<\/p>\n<p>Sun, Austin (2023)<br \/>\nThesis: Molecular Mechanisms of Drug Transport at the Blood-CSF Barrier Revealed by Live Tissue Imaging and Quantitative Fluorescence Microscopy<br \/>\nThesis Advisor: Joanne Wang, Ph.D.<\/p>\n<p>Tieu, Taryn (2025)<br \/>\nThesis: Pharmacological profiling of investigational antiseizure medicines in female CF-1 mice<br \/>\nThesis Advisor: Melissa Barker-Haliski, Ph.D.<\/p>\n<p>Tay, Suzanne (2009)<br \/>\nThesis:<br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Thatcher, Jayne (2010)<br \/>\nThesis: Characterization of the retinoic acid hydroxylases CYP26A1 and CYP26B1: catalytic activity, tissue expression, and ligand selectivity<br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Templeton, Ian (2008)<br \/>\nThesis: Contribution of itraconazole and its metabolites to in vivo CYP3A4 inhibition<br \/>\nThesis Advisor: Kenneth Thummel,Ph.D.<\/p>\n<p>Thomassen, David (1989)<br \/>\nThesis: Mechanisms of Pulegone Hepatotoxicity<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Thummel, Kenneth (1987)<br \/>\nThesis: Mechanism by which Ethanol Protects Against Acetaminophen Hepatotoxicity<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Tsang, Tim (2025)<br \/>\nThesis: <span id=\"ctl00_ContentPlaceHolderMain_LabelThesisTitle\">Regulation of Human Renal Drug Transporters by Inflammatory Cytokines and Pregnancy-related Hormones in Primary Proximal Tubular Epithelial Cells<\/span><br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D. &amp; Edward Kelly, Ph.D.<\/p>\n<p>Tuntland, Tove (1996)<br \/>\nThesis: Mechanisms of Transfer of Anti-HIV Dideoxynucleoside Drugs Across the Placenta and the Blood-CSF Barrier<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Voellinger, Jenna (2015)<br \/>\nThesis: Molecular and Cellular Characterization of Human Embryonic Stem Cell Derived Hepatocytes<br \/>\nThesis Advisor: Edward Kelly, Ph.D.<\/p>\n<p>Walker, Alysa (2010)<br \/>\nThesis: Mechanisms by which Pregnancy Decreases Rat CYP1A2 Activity and Expression<br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Wang, Ji-Ping (1992) Deceased<br \/>\nThesis: Renal Tublar Secretion of Ticarcillin in Cystic Fibrosis<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Wang, Kai (2024)<br \/>\nThesis: Effect of Pro-inflammatory Cytokines on Intestinal Drug Transporters in Human Enteroid Monolayers<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Weber, Allan (1999)<br \/>\nThesis: Induction of P450 (CYP3A6) in Rabbits by the Fifamycins, Rifabutin, and Rifampin, and Administration of Tobramycin by Aerosolization to Patients with Cystic Fibrosis<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Weber, Elijah (2018)<br \/>\nThesis: Development of a Microphysiological Model of the Kidney Proximal Tubule and Application in Predictive Toxicity Testing of Polymyxin Antibiotics<br \/>\nThesis Advisor: Edward Kelly, Ph.D.<\/p>\n<p>Wedlund, Peter (1981)<br \/>\nThesis: Carbamazepine: Mechanism of Autoinduction of Clearance in Rhesus Monkey and Rat<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>White, Catherine(1985)<br \/>\nThesis: In Vitro Pharmacokinetics\/Pharmacodynamic Studies of Beta-Lactam Efficacy<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Wilson, John (1984)<br \/>\nThesis: Pharmacokinetics and Metabolic Aspects of Acetaminophen Toxicity in Man and Swiss-Webster Mice<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Winter, Helen (1998)<br \/>\nThesis: Strategies to Reduce Arylamire Drug Toxicity in People with AIDS<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Woodahl, Erica Lynn (2004)<br \/>\nGenetic variations in the multidrug resistance gene ( MDR1): Impact on drug delivery and disposition<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Wright, Catherine (2026)<br \/>\nAssociation of Gemcitabine and Paclitaxel to Drug-combination Nanoparticles Leads to Long-acting Pharmacokinetics, Ehances Plasma and Pancreatic Drug Exposure Relating to Tumor Rregression: Interventional Studies in an Orthotopic Pancreatic Tumor Model<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Wurden (Johnson), Colleen (2000)<br \/>\nThesis: Metabolism of Carbamazepine and Inhibitory Drug Interactions<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Xu, Guangyuan (2024)<br \/>\nThesis: Analytical methods to determine the degree of drug association for complex injectable drug-combination particles containing multiple drug substances<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Xu, Xiaolin (2026)<br \/>\nThesis: <span id=\"ctl00_ContentPlaceHolderMain_LabelThesisTitle\">Drug Combination Nanoparticles Carrying Fixed-Dose Gemcitabine and Paclitaxel: Formation Mechanisms Influencing PKDM and Efficacy in Triple-negative Breast Cancer Mouse Models<\/span><br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Xu, Yang (2005)<br \/>\nThesis: Regulation of Intestinal CYP3A4 Expression and Metabolism of 1Alpha, 25-Dihydroxyvitamin D3<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Xu, Yun (2004)<br \/>\nThesis: Mechanistic Studies on the Differences between in vitro and in vivo Inhibition Potencies of Fluvoxamine towards Various Cytochrome P450S<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Yabut, King (2024)<br \/>\nThesis: Human Liver Fatty Acid Binding Protein (FABP1) Alters THC Metabolism by CYP2C9, CYP3A4 and CYP2C19 in vitro<br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Yadav, Aprajita (2025)<br \/>\nThesis: A Systems Approach to Vitamin A Homeostasis: Integrating Proteomics, Physiology, and Hormonal Modulation of RBP4 and TTR<br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Yang, Bing-Bing (Bonnie) (1992)<br \/>\nThesis: Hepatic Uptake of S-Propranolol in Uremia<br \/>\nThesis Advisor: Danny Shen, Ph.D.<\/p>\n<p>Yao, Caiping (2001)<br \/>\nThesis: Comparison of In Vitro and In Vivo Inhibition Potencies of Fluvoxamine Toward CYP1AZ and CYP2C19<br \/>\nThesis Advisor: Ren\u00e9 Levy, Ph.D.<\/p>\n<p>Yin, Mengyue (Melody) (2023)<br \/>\nThesis: Prediction of Transporter-Based Drug Clearances and Tissue Concentrations: Relative Expression Factor Approach and Protein-Mediated Uptake Effect<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Yimam, Mesfin (2004)<br \/>\nThesis: Identification and Characterization of Primate P-Glycoprotein<br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Yu, Jesse (2020)<br \/>\nThesis: Targeted drug combination nanoparticles enhance exposure of gemcitabine and paclitaxel in breast cancer cells: A novel approach to treat metastasis<br \/>\nThesis: Rodney Ho, Ph.D.<\/p>\n<p>Zhang, Cindy (2024)<br \/>\nThesis: Oral Drug Pharmacokinetics and Treatment Effects in Populations Affected by Diarrheal Diseases<br \/>\nThesis advisor: Samuel Arnold, Ph.D.<\/p>\n<p>Zhang,Haeyoung (2020)<br \/>\nThesis: Characterization of Interindividual Variability and Differential Tissue Abundance of UGT2B17: Discovery of a Potential Biomarker and Drug Interaction Prediction<br \/>\nThesis advisor: Kenneth E Thummel, Ph.D.<\/p>\n<p>Zhang, Huixia (2009)<br \/>\nThesis: Mechanisms by which pregnancy increases the clearance of the anti-HIV protease inhibitor, nelfinavir<br \/>\nThesis Advisor: Jashvant Unadkat, Ph.D.<\/p>\n<p>Zhang, Yi (2007)<br \/>\nThesis: Potential Impact of Breast Cancer Resistance Protein on Drug Disposition during Pregnancy<br \/>\nThesis Advisor: Qingcheng Mao, Ph.D.<\/p>\n<p>Zhao, Ping (2002)<br \/>\nThesis: The Influence of Alcohol on Acetaminophen Hepatotoxicity: CYP2E1 Induction and Selective Mitochondrial Glutathione Depletion<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n<p>Zhao, Yuqian (2023)<br \/>\nThesis: <span class=\"ui-provider ed bbc bbd bbe bbf bbg bbh bbi bbj bbk bbl bbm bbn bbo bbp bbq bbr bbs bbt bbu bbv bbw bbx bby bbz bca bcb bcc bcd bce bcf bcg bch bci bcj\" dir=\"ltr\">Determining the Effect of Isotretinoin on CYP2D6 and CYP3A4 Activity in Patients with Severe Acne<\/span><br \/>\nThesis Advisor: Nina Isoherranen, Ph.D.<\/p>\n<p>Zheng, Emily (2010)<br \/>\nThesis: Human PXR-mediated Dysregulation of 1,25-dihydroxyvitamin D3 function: A Possible Mechanism of Drug-induced Osteomalacia<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Zheng, Songmao (2012)<br \/>\nThesis: The Impact of CYP3A5 Variation and Pregnancy on the Metabolic Disposition of Calcineurin Inhibitors Thesis<br \/>\nThesis Advisor: Kenneth Thummel, Ph.D.<\/p>\n<p>Zhou, Lin (2009)<br \/>\nThesis: Glyburide Disposition during Pregnancy: the Role of BCRP(ABCG2) Transporter and Cytochrome P450 Enzymes<br \/>\nThesis Advisor: Qingcheng Mao, Ph.D.<\/p>\n<p>Zhou, Mingyan (2007)<br \/>\nThesis: Structural and Functional Analysis of a Novel Organic Cation\/Monoamine Transporter PMAT in SLC29 family<br \/>\nThesis Advisor: Joanne Wang , Ph.D.<\/p>\n<p>Zhu, Linxi (2021)<br \/>\nThesis: <span data-olk-copy-source=\"MessageBody\">Drug combination nanoparticles targeted to ICAM-1 on breast cancer cells enhance cellular drug exposure in vitro and in mouse model<\/span><br \/>\nThesis Advisor: Rodney Ho, Ph.D.<\/p>\n<p>Zimmerman, Cheryl (1983)<br \/>\nThesis: Pharmacokinetics and Metabolism of Methotrexate in Skin<br \/>\nThesis Advisor: John Slattery, Ph.D.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Adkison, Kimberly (1994) Thesis: Central Nervous System Transport of Valproic Acid Thesis Advisor: Danny Shen, Ph.D. Alade, Nathan (2023) Thesis: Precision Approaches for Assessing Complex Pharmacogenomic Traits in Vitamin K Metabolism Thesis Advisor: Kenneth 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