PUBLICATIONS


Original Peer Reviewed Journal Articles

Welikson R, Kaestner S, Reinecke H, Hauschka SD. Human umbilical vein endothelial cells fuse with cardiomyocytes but do not activate cardiac gene expression. Journal of Molecular and Cellular Cardiology 40(4); 520-528, 2006. [Medline]  [PDF].

Reinecke H, Minami E, Virag JI, Murry CE. Gene transfer of connexin43 into skeletal muscle. Human Gene Therapy 15 (7), 627-636, 2004.   [PDF].

Reinecke H
, Minami E, Poppa V, Murry CE.
Evidence for fusion between cardiac and skeletal muscle cells. Circulation Research 94;  e56-e60, 2004. [Medline]  [PDF].

Murry CE, Soonpaa MH, Reinecke H, Nakijima H, Nakijima HO, Rubart M, Pasumarthi KBS, Virag JI, Bartelmez SH, Poppa V, Bradford G, Dowell JD, Williams DA, Field LJ. Absence of cardiac transdifferentiation after direct injection of adult hematopoietic stem cells into myocardial infarcts. Nature 428; 664-668, 2004. [Medline]  [PDF]  [Data supplement].

Shi D, Reinecke H, Murry CE, Torok-Storb B. Myogenic fusion of human bone marrow stromal cells, but not hematopoietic cells. Blood 104 (1); 290-294, 2004. [Medline]  [PDF].

Reinecke H, Poppa V, Murry CE. Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting. Journal of Molecular and Cellular Cardiology 34 (2); 241-249, 2002. [Medline]  [PDF].

McDevitt TC, Angello JC, Whitney ML, Reinecke H, Hauschka SD, Murry CE, Stayton PS. In vitro generation of differentiated cardiac myofibers on micropatterned laminin surfaces.  Biomaterials Research 60 (3); 472-479, 2002. [Medline]  [PDF].

Whitney ML, Otto KG, Blau CA, Reinecke H, Murry CE. Control of myoblast proliferation with a synthetic ligand. Journal of Biological Chemistry 276 (44), 41191-41196, 2001. [Medline].

Reinecke H and Murry CE. Transmural replacement of myocardium after skeletal myoblast grafting into the heart. Too much of a good thing? Cardiovascular Pathology 9 (6); 337-344, 2000. [Medline]  [PDF].

Imanishi T, Murry CE, Reinecke H, Hano T, Nishio I, Liles WC, Hofsta L, Kim K, O'Brien KD, Schwartz SM, Han DK. Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues. Cardiovascular Research 48; 101-110, 2000. [Medline].

Reinecke H, MacDonald GH, Hauschka SD, Murry CE. Electromechanical coupling between skeletal and cardiac muscle: implications for infarct repair. Journal of Cell Biology, 149 (3); 731-740, 2000. [Medline]  [PDF].

Reinecke H, Zhang M, Bartosek T, Murry CE. Survival, integration, and differentiation of cardiomyocyte grafts. A study in normal and injured rat hearts. Circulation, 100; 193-202, 1999. [Medline]  [PDF].

Reinecke H, Vetter R, Drexler H. Effects of alpha-adrenergic stimulation on the sarcolemmal Na+/Ca2+-exchanger in adult rat ventricular cardiocytes. Cardiovascular Research 36; 216-222, 1997. [Medline]  [PDF].

Reinecke H, Studer R, Vetter R, Holtz J, Drexler H. Cardiac Na+/Ca2+ exchange activity in patients with end-stage heart failure. Cardiovascular Research 31; 48-54, 1996. [Medline]  [PDF].

Reinecke H, Studer R, Vetter R, Just H, Holtz J, Drexler H. Role of the cardiac sarcolemmal Na+/Ca2+ exchanger in end-stage human heart failure. Annals of the New York Academy of the Science, 779; 543-545, 1996. [Medline].

Vetter R, Studer R, Reinecke H, Kolár F, Ostádalová I, Drexler H. Reciprocal changes in the post-natal expression of the sarcolemmal Na+/Ca2+ exchanger and SERCA2 in rat heart. Journal of Molecular and Cellular Cardiology 27; 1689-1701, 1995. [Medline].

Studer R, Reinecke H, Bilger J, Eschenhagen T, Böhm M, Hasenfuss G, Just H, Holtz J, Drexler H. Gene expression of the cardiac sodium-calcium exchanger in end-stage human heart failure. Circulation Research 75:443-453, 1994. [Medline].

Studer R, Reinecke H, Müller B, Holtz J, Just H, Drexler H. Increased angiotensin-I converting enzyme gene expression in the failing human heart. Journal of Clinical Investigation 94:301-310, 1994. [Medline].

Hasenfuss G, Reinecke H, Studer R, Meyer M, Pieske B, Holtz J, Holubarsch C, Posival H, Just H, Drexler H. Relation between myocardial sarcoplasmic reticulum calcium-ATPase in failing and nonfailing human myocardium. Circulation Research 75:434-442, 1994. [Medline].
 

More Murry Lab Publications

Virag JI and Murry CE. Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. American Journal of Pathology 163(6):2433-2440, 2003. [Medline].
Ismail JA, Poppa V, Kemper LE, Scatena M, Giachelli CM, Coffin JD, Murry CE. Immunohistologic labeling of murine endothelium. Cardiovascular Pathology 12(2):82-90, 2003. [Medline].

Laflamme MA, Myerson D, Saffitz JE, Murry CE. Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts. Circulation Research 90(6): 634-640, 2002. [Medline].

Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, Murry CE. Cardiomyocyte grafting for cardiac repair: Graft cell death and anti-death strategies. Journal of Molecular and Cellular Cardiology, 33:907-921, 2001. [Medline].


Review Articles, Editorials, Book Chapters

Murry CE, Reinecke H, Pabon LM. Regeneration gaps: Observations on stem cells and cardiac repair. Journal of the American College of Cardiology 47(9); 1777-1785, 2006.  [Medline]  [PDF].

Murry CE and Reinecke H. How to keep cellular grafts alive and synchronise them with rest of the heart? Dialogues in Cardiovascular Medicine (DCVM) 8(3), 2003.

Minami E, Reinecke H, Murry CE. Skeletal muscle meets cardiac muscle: Friends or foes? Journal of the American College of Cardiology, 41(7):1084-1086, 2003.  [PDF].

Reinecke H and Murry CE. Cell grafting for cardiac repair. In Cardiac Cell and Gene Transfer: Principles, Protocols, and Applications.  Metzger, Joseph M. (ed.; University of Michigan Medical School, Ann Arbor, MI). Methods in Molecular Biology 219; 97-112, 2003. Humana Press. [Medline].

Reinecke H, Murry CE. Taking the death toll after cardiomyocyte grafting: a reminder of the importance of quantitative biology. Journal of Molecular and Cellular Cardiology 34 (3); 251-253, 2002. [Medline]  [PDF].

Murry CE, Whitney ML, Reinecke H. Muscle cell grafting for the treatment and prevention of heart failure. Journal of Cardiac Failure 8 (6 Suppl); S532-541, 2002. [Medline]  [PDF].

Murry CE, Whitney ML, Laflamme MA, Reinecke H, Field LJ. Cellular therapies for myocardial infarct repair. Cold Spring Harb Symp Quant Biol.; 67:519-26, 2002.

Reinecke H
, MacDonald GH, Hauschka SD, Murry CE. Cardiomyocytes can induce rhythmic contraction of skeletal muscle cells. Potential use for infarct repair. In Molecular Approaches to Heart Failure Therapy. G. Hasenfuss, E. Marbán (eds), Steinkopff Verlag (publ.), 316-332, 2000.

Murry CE, Zhang M, Reinecke H. Myocardial infarction, infarct repair, and strategies for muscle regeneration. In Molecular Approaches to Heart Failure Therapy. G. Hasenfuss, E. Marbán (eds), Steinkopff Verlag (publ.), 298-315, 2000.

Studer R, Reinecke H, Vetter R, Holtz J, Drexler H. Expression and function of the cardiac Na+/Ca2+ exchanger in postnatal development of the rat, in experimental-induced cardiac hypertrophy, and in the failing human heart. Basic Research in Cardiology 92: Suppl. 1:53-58, 1997. [Medline].

Hasenfuss G, Reinecke H, Studer R, Pieske B, Meyer M, Drexler H, Just H. Calcium cycling proteins and force-frequency relations in heart failure. Basic Research in Cardiology 91: Suppl. 2:17-22, 1996. [Medline].

Holtz J, Studer R, Reinecke H, Just H, Drexler H. Modulation of sarcoplasmic reticulum Ca2+-ATPase in cardiac hypertrophy by angiotensin converting enzyme? Basic Research in Cardiology 87:Suppl. 2:191-204, 1992. [Medline].


Presentations at the Annual Meeting of the American Heart Association (AHA)

Ueno S, Kohn AD, Golob JL, Pabon L, Reinecke H, Moon RT, Murry CE. Wnt-3a accelerates the onset of cardiogenesis and Wnt-11 enhances the differentiation of mouse embryonic stem cells into cardiac myocytes. Poster presentation at the Annual Meeting of the American Heart Association (AHA) in Dallas, Texas, November 2005.

Reinecke H, Minami E, Murry CE. Evidence for fusion between cardiac and skeletal muscle cells. Circulation Vol 102, No 17, Abs. #1289, Suppl., 2003.

Reinecke H, Murry CE. Transdifferentiation of skeletal muscle stem cells after grafting into the heart? Circulation Vol 102, No 18, Abs. #3158, Suppl., 2000.

Imanishi T, Murry CE, Reinecke H, Hano T, Han D, Schwartz SM. Cellular Flip is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues. Circulation Vol 102, No 18, Abs. #1030, Suppl., 2000.

Reinecke H, Murry CE. Electromechanical coupling between skeletal and cardiac muscle: Implications for infarct repair. Circulation Vol 98, No 17, Abs. #3975, Suppl., 1998.

Reinecke H, Bartosek T, Murry CE. Integration and differentiation of cardiocytes after grafting into normal and injured myocardium. Circulation Vol 96, No 8, Abs. #100, Suppl., 1997.

Reinecke H, Studer R, Zierhut W, Drexler H. Down-regulation of the sarcoplasmatic reticulum (SR) Ca2+ ATPase mRNA by angiotensin-II in adult rat cardiomyocytes. Circulation Vol 92, No 8, Abs. #1342, Suppl., 1995.

Reinecke H, Studer R, Mueller B, Kaestner S, Drexler H. Gene expression of the angiotensin-I converting enzyme (ACE) in adult cardiomyocytes of the rat. Circulation Vol 90, No 4, Part 2, Abs. #3116, Suppl., 1994.

Hasenfuss G, Meyer M, Schillinger W, Pieske B, Scheffler A, Holubarsch C, Reinecke H. Expression of sarcoplasmic reticulum proteins in failing and nonfailing human myocardium. Circulation Vol 90, No 4, Part 2, Abs. #1160, Suppl., 1994.

Reinecke H, Studer R, Vetter R, Just H, Holtz J, Drexler H. Enhanced expression and function of the cardiac Na+/Ca2+-exchanger in end-stage human heart failure. Circulation Vol 88, No 4, Part 2, Abs. #2190, Suppl., 1993.

Studer R, Reinecke H, Vetter R, Holtz J, Drexler H. Enhanced expression and function of the Na+/Ca2+-exchanger in rat left ventricular hypertrophy and in myocard of neonatal rats. Circulation Vol 88, No 4, Part 2, Abs. #0452, Suppl., 1993.

Reinecke H, Studer R, Philipson KD, Bilger J, Eschenhagen T, Boehm M, Just H, Holtz J, Drexler H. Myocardial gene-expression of Na+/Ca2+-exchanger and sarcoplasmic-reticulum Ca2+-ATPase in human heart failure. Circulation Vol 86, No 4, Abs. #3423, Suppl., 1992.

Studer R, Mueller B, Reinecke H, Just H, Holtz J, Drexler H. Quantified RNA polymerase chain reaction demonstrates augmented gene expression of angiotensin converting enzyme in ventricles of patients with heart failure. Circulation Vol 86, No 4, Abs. #0475, Suppl., 1992.

Allgeier J, Goetz RM, Studer R, Reinecke H, Holtz J. Involvement of bradykinin in the cardioreparation by chronic quinapril in rats with hypertensive left-ventricular hypertrophy. Circulation Vol 86, No 4, Abs. #1308, Suppl., 1992.

Holtz J, Goetz RM, Reinecke H, Studer R. Myocardial phenotype changes in hypertensive cardiac hypertrophy: phenotype normalization with normalization of wall stress inspite of persisting hypertension and hypertrophy. Circulation Vol 86, No 4, Abs. #0374, Suppl., 1992.


Presentations at the Annual Meeting of the European Society of Cardiology (ESC)

Reinecke H, Studer R, Müller B, Holtz J, Drexler H, Just H. Gene expression of the angiotensin I converting enzyme in adult cardiomyocytes of the rat. European Heart Journal Vol 15 (Abstract Suppl.), Abs. #P1466, 1994.

Reinecke H, Studer R, Vetter R, Holtz J, Drexler H. Enhanced expression and function of the cardiac Na+/Ca2+-exchanger in end-stage human heart failure. European Heart Journal Vol 15 (Abstract Suppl.), Abs. #P1122, 1994.

Studer R, Kästner S, Reinecke H, Holtz J, Drexler H, Just H. Myocardial gene expression of NO synthase in ischemic and dilative cardiomyopathy. European Heart Journal Vol 15 (Abstract Suppl.), Abs. #P625, 1994.

Studer R, Sütsch G, Reinecke H, Müller B, Hess OM, Holtz J, Drexler H. Increased angiotensin I converting enzyme gene expression in the failing human heart. European Heart Journal Vol 15 (Abstract Suppl.), Abs. #P618, 1994.


Home
CV
Steffi's Page
Al's Page

Last updated: April 10, 2004.