Welcome to the Hoofnagle Lab!

Mass Spectrometry for Patient Care

The Hoofnagle Laboratory has helped pioneer the use of LC-MS/MS for proteins in the care of patients and we are continuing to develop novel assays for the clinical laboratory.

The laboratory mainly focuses on the application of proteomics and metabolomics on the investigation of vitamin D metabolism, lipid biology, chronic kidney disease, diabetes, nutrition, Alzheimer's disease, cancer and anti-doping. Most of our assays utilize targeted mass spectrometry to precisely quantify proteins or small molecules in human and mouse samples. These assays have been deployed in large clinical research studies and clinical trials.